Hormone Therapy News

Common antibiotic drugs — even those that do not induce enzymes — may reduce the effectiveness of hormonal contraceptives and lead to unintended pregnancy, according to study data published in BMJ Evidence-Based Medicine.

Youths who seek gender-affirming medical care at age 15 years and older and further along in puberty are more likely than their younger peers to report depression, self-harm and suicidal thoughts, researchers reported in Pediatrics.

Early menopausal women experienced different changes in cognitive health imaging biomarkers based on route of delivery of hormone therapy vs. placebo in the Kronos Early Estrogen Prevention Study, according to a speaker.

Frequent hot flashes are associated with indicators of cardiovascular disease among midlife and older women; poor sleep and trauma history may act synergistically with vasomotor symptoms to further increase risk, according to a speaker.

A 1 mg dose of estradiol reduced biomarkers of inflammation tied to atherosclerosis in postmenopausal women — particularly those in early menopause — participating in the Early vs. Late Intervention Trial with Estradiol.

Fetal estrogens, considered “weak” steroid hormones detectable only during pregnancy, may improve the risk-benefit profile for the treatment of menopausal symptoms compared with current therapies, according to a speaker.

When talking about treating children with unequivocal growth hormone deficiency, who in the absence of GH therapy have little chance of achieving normal adult stature, the overwhelming majority of endocrinologists would say yes, even though GH has some documented risks and may have some potential theoretical risks. With a condition like idiopathic short statue, the benefit of GH therapy, in general, is not as obvious as with GH deficiency. That forces one to possibly reassess the risk vs. benefits.

Growth hormone deficiency, characterized by the inadequate secretion of GH from the anterior pituitary gland, is a rare disorder among U.S. children, with an estimated prevalence of 1 in 3,500.

Exposure to the endocrine-disrupting chemical bisphenol A was significantly and positively associated with all-cause mortality in U.S. adults, according to an analysis of National Health and Nutrition Examination Survey data.

Menopause can be a good time to start addressing CVD risk reduction even though it should be discussed way before then, according to a presentation at the virtual Heart in Diabetes Conference.