Hormone Therapy News

Gonadotropin-releasing hormone analogue use was not associated with increased use of subsequent gender-affirming hormones among transgender and gender-diverse youths, according to a retrospective cohort study published in JAMA Network Open.

Postmenopausal women with moderate to severe genitourinary syndrome experienced small but significant increases in serum estradiol after using vaginal estradiol tablets for 12 weeks, according to a post hoc analysis in JAMA Network Open.

PHILADELPHIA — Taking an “anatomy inventory” during visits can help cultivate a more supportive environment for transgender and non-binary patients to discuss their gender identity and the need for organ-specific care, a presenter here said.

The placebo effect may play a role in the results of randomized controlled trials investigating medications for vasomotor symptoms, according to a meta-analysis published in Menopause.

The decision to ban gender-affirming care for youth in Florida will cause “irrevocable harm,” ACP President Ryan D. Mire, MD, MACP, said in a press release.

Most transgender adolescents who used pubertal blockers and were later prescribed gender-affirming hormone therapy in the Netherlands continued to use hormones as adults, according to data published in The Lancet Child & Adolescent Health.

Sex-chromosomes and rapid changes in sex hormones during adolescence may drive changes in regulatory T-cell frequency and function, according to data published in The Lancet Rheumatology.

The U.S. Preventive Services Task Force has released two final recommendations on the use of hormone therapy for the primary prevention of chronic conditions in postmenopausal people.

Most transgender boys reach their predicted adult height after treatment with gonadotropin-releasing hormone analogues and testosterone therapy, according to data published in The Journal of Clinical Endocrinology & Metabolism.

About 30% of a cohort of gender-diverse youths had low whole-body bone mineral density z scores prior to initiation of puberty blockers or gender-affirming hormones, according to findings published in Transgender Health.