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Cardiometabolic Disorders News
Top-line results: Finerenone reduces events in certain patients with heart failure
Bayer announced positive top-line results for the FINEARTS-HF trial of finerenone, in which the drug reduced risk for cardiovascular death and heart failure events in patients with HF with preserved or mildly reduced ejection fraction.
Prescription fills for semaglutide dramatically increase from 2021 to 2023
The number of monthly prescription fills for semaglutide increased by 442% from 2021 to 2023, according to a research letter published in JAMA Health Forum.
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Duodenal mucosal resurfacing granted FDA breakthrough label for weight loss maintenance
The FDA granted breakthrough device designation for an endoscopic procedure that resurfaces the duodenum lining to allow for weight maintenance after discontinuation of a GLP-1 receptor agonist, according to an industry press release.
New risk calculator could reduce eligibility for statins, BP drugs by 16 million US adults
Using the American Heart Association’s new PREVENT risk calculator would mean reducing eligibility for statin and/or antihypertensive therapy by approximately 16 million U.S. adults, researchers reported in JAMA.
FDA warns of adverse events due to overdosing of compounded semaglutide
The FDA is warning providers and patients that dosing errors with compounded injectable semaglutide may be leading to adverse events, according to a press release.
Q&A: New initiative to address CKM syndrome, affecting millions in the US
In October 2023, the American Heart Association unveiled the term cardiovascular-kidney-metabolic syndrome to reflect the connection between metabolic and renal conditions associated with risk for heart disease.
Risk for heart, liver disease may vary between PCOS subtypes
Women with polycystic ovary syndrome and high androgen levels may have a higher risk for liver disease than those with PCOS and normal androgen levels, according to an analysis of UK Biobank data.
Weight-loss surgery appears to benefit patients with heart failure, obesity
In a single-center cohort of patients with heart failure and obesity, weight-loss surgery led to improved clinical outcomes including reduced BMI and HbA1c and less reliance on diuretics, researchers reported.
Obesity in young adulthood linked to adverse heart structure, function later in life
People with excess adiposity in young adulthood were more likely to have adverse cardiac structure and function later in life compared with people without it, researchers reported in the European Heart Journal.
MASH therapies still needed despite boom in GLP-1 use in liver disease
GLP-1 receptor agonist use in diabetes and obesity has soared, and indications are now expanding into liver diseases, specifically metabolic dysfunction-associated steatohepatitis. However, the jury is still out on its benefits.
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Headline News
Burnout, withdrawal remain ‘alarmingly high’ among physicians and residents
September 17, 20242 min read -
Headline News
Over one-third of adults not planning on receiving recommended vaccines this fall
September 18, 20242 min read -
Headline News
Popular home BP devices unable to provide accurate readings for millions due to sizing
September 19, 20242 min read