Cardiometabolic Disorders News

SAN DIEGO — Adults with type 1 diabetes may experience increases in glucose and insulin resistance in the days after receiving a COVID-19 booster vaccine, according to a presenter at the American Diabetes Association Scientific Sessions.

Among people with diabetes, higher loneliness scores, but not isolation scores, were associated with greater risk for CVD, suggesting the quality but not quantity of relationships can impact disease risk, researchers reported.

SAN DIEGO — Adults with overweight or obesity lost up to 18.7% of their body weight at 46 weeks with a glucagon/GLP-1 dual agonist, according to a speaker.

In a trial of more than 20,000 older adults, vitamin D supplementation trended toward reducing risk for major CV events in older adults compared with placebo, a finding differing from previous studies.

Researchers observed no increased risk for new-onset diabetes among IMPROVE-IT participants assigned to ezetimibe plus statin therapy vs. statin monotherapy, according to a research letter.

In adults with obesity and obstructive sleep apnea, bariatric surgery was associated with reduced risk for major adverse CV events compared with no surgery, researchers reported.

SAN DIEGO — Adults with obesity and type 2 diabetes who undergo bariatric or metabolic surgery have a lower HbA1c and greater weight loss than those who did not undergo surgery at 7 and 12 years of follow-up, according to trial data.

SAN DIEGO — Matthias Tschöp, MD, has played a major role in the recent influx of novel therapies for the treatment of diabetes and obesity.

SAN DIEGO — Adults with obesity who received the highest dose of a once-weekly injection of retatrutide lost an average of 24.2% of their body weight at 48 weeks compared with placebo, data from a phase 2 study show.

SAN DIEGO — Oral semaglutide 50 mg induces more than 15% weight loss in adults with obesity at 68 weeks and can reduce HbA1c by 2 percentage points at 52 weeks for those with type 2 diabetes, according to data from two phase 3 trials.