Bone/Mineral Metabolism News

A cross-sectional analysis of national survey data shows that age at peak bone mineral density attainment varies by sex and skeletal site, with women reaching peak BMD at all sites up to 4 years earlier than men, according to findings published in Bone.

Conservative estimates suggest that the prevalence of X-linked hypophosphatemia, or XLH, a rare form of rickets, has more than tripled in the past 25 years in the United Kingdom, with researchers noting a concerning reduction in survival among patients with the disease.

ATLANTA — Romosozumab increases bone mineral density among patients with osteoporosis across different levels of renal function, according to a presenter at ACR/ARP 2019.

Young men who reported smoking at least 21 cigarettes per day or drinking heavily were up to 70% more likely to experience a fracture in middle-age when compared with nonsmokers or men who reported moderate alcohol consumption, according to findings published in the Journal of Bone and Mineral Research.

PHILADELPHIA — Interventions with vitamin D or omega-3 failed to reduce rates of first heart failure hospitalization in a large cohort of healthy adults, although researchers observed a benefit for recurrent HF hospitalization with fish oil supplementation, according to findings from an ancillary study of the VITAL trial presented at the American Heart Association Scientific Sessions.

Older adults with subclinical hypothyroidism assigned 1 year of levothyroxine therapy experienced no adverse changes in any bone parameters compared with similar adults assigned placebo, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Older adults who discontinue denosumab are at greater risk for major osteoporotic fractures and multiple vertebral fractures than those who persist with treatment, according to findings from a real-world database analysis published in Bone.

ATLANTA — The 2019 iteration of the ACR/ARP Great Debate tackled the issue of whether anabolic therapies are appropriate for patients with glucocorticoid-induced osteoporosis.

Postmenopausal women who report sleeping less than 5 hours per night are more likely to develop low bone mineral density at all major sites and are at increased risk for osteoporosis at the hip and spine, according to findings published in the Journal of Bone and Mineral Research.

WASHINGTON — For patients on hemodialysis who eat rice as a main source of calories, low-protein rice plus low-phosphorus whey can reduce serum phosphorus and improve serum albumin, according to study results presented at ASN Kidney Week.