Bone/Mineral Metabolism News

An analysis of three fracture risk assessment tools revealed that major osteoporotic fracture risk varied by chronic kidney disease status, according to findings published in the Journal of Bone and Mineral Research.

Abnormal bony projections in joint spaces and at attachments of tendons or ligaments were common among a small cohort of middle-aged adults with X-linked hypophosphatemia, progressively impairing joint range of motion, gait and physical function and warranting a longitudinal care plan, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

The Endocrine Society updated its osteoporosis clinical practice guideline to include recommendations for romosozumab, noting that the monthly injection therapy is an “effective option” for postmenopausal women at high risk for fracture, according to a society press release.

A post hoc analysis of five randomized controlled trials suggests that older adults with osteoporosis assigned denosumab therapy were 20% less likely to experience a fall during follow-up compared with those assigned placebo, according to findings published in the Journal of Bone and Mineral Research.

Although causality is difficult to prove definitively, mounting evidence suggests adverse health consequences of endocrine-disrupting among humans. Recent research links these ubiquitous compounds to pediatric obesity, diabetes, osteoporosis and more.

Prolonged use of menopausal hormone therapy is associated with high skeletal muscle mass and a low prevalence of sarcopenia among postmenopausal women, according to findings published in Menopause.

Combining indices of frailty and trabecular bone score did not yield improved predictive accuracy for major osteoporotic fracture risk when compared with frailty alone or trabecular bone score alone, according to findings published in the Journal of Bone and Mineral Research.

Larger mid-arm muscle circumference is associated with lower risk for osteoporosis among men, according to findings published in the Archives of Gerontology and Geriatrics.

The analgesic medication tramadol was associated with a higher risk for hip fracture compared with codeine and commonly used NSAIDs, according to findings from a population-based study.

Adults with moderate to severe chronic kidney disease at high risk for fracture were no more likely to die of any cause when prescribed bisphosphonate therapy compared with adults with CKD who were not prescribed a bisphosphonate, according to findings from a population-based study published in the Journal of Bone and Mineral Research.