Bone/Mineral Metabolism News

Adults with type 1 diabetes for at least 25 years have lower areal bone mineral density compared with those without diabetes, and diabetic neuropathy is linked to further BMD declines in the ultradistal tibia, according to study data.

Adults with osteoporosis have a higher risk for developing osteonecrosis of the jaw with denosumab therapy compared with bisphosphonates, according to study findings published in the Journal of Bone and Mineral Research.

Among women aged 40 to 64 years, a recent major osteoporotic fracture was associated with increased risk for a repeat fracture at 10 years, with highest risk within the first 2 years of the fracture, according to study data.

Compared with other first-line osteoporosis treatments, alendronate therapy yielded an increased risk for depression and anxiety, according to an analysis of adverse events reports.

Older adults with higher levels of saturated bone marrow lipids have a higher risk for fractures, whereas those with more unsaturated marrow lipids have a lower fracture risk, according to study findings.

U.S. Army recruits taking a daily calcium and vitamin D supplement during basic training had no change in tibial microarchitecture compared with placebo, according to study data published in Bone.

Muscle strength and physical performance measures may improve fracture risk prediction for older men and should be incorporated into fracture prediction models, according to study findings.

A supplement of Vitamin D2 may improve insulin sensitivity and slow the increase of HbA1c for children and adolescents with new-onset type 1 diabetes, according to study findings published in the Journal of the Endocrine Society.

The reduced risks for osteoporotic and hip fractures with bisphosphonate therapy outweigh increased risk for atypical femur fractures for older women, according to study finding published in Bone.

High levels of body fat are associated with a lower bone mineral density, with the association more pronounced in men compared with women, according to study data published in The Journal of Clinical Endocrinology & Metabolism.