Adrenal News

A 34-year-old woman was referred for a four-year history of episodic hypertension, palpitations, flushing and diaphoresis.

Prepubertal children with premature adrenarche had higher bone mineral density when compared with healthy children in a new cross-sectional study. However, bone size-adjusted BMD or height-adjusted BMD was not significantly different between the two groups.

Researchers have identified an additional deleterious effect of glucocorticoid therapy in women treated for Cushing’s syndrome.

New observational Norwegian registry data reveal that Addison’s disease is almost exclusively autoimmune, and is associated with high autoimmune comorbidity.

Researchers have discovered a high prevalence of vertebral fractures and low bone mineral density among eugonadal men with adrenal incidentalomas.

Late-pubertal diaphyseal bone mass, modeling and strength were predicted by renal excretion levels of androstenediol that were collected from healthy adolescents two years before puberty onset.

A 35-year-old obese black woman with hypertension resistant to triple antihypertensive therapy including lisinopril 40 mg daily, atenolol 100 mg twice daily and hydrochlorothiazide 25 mg daily was referred to the endocrine clinic for the evaluation of an endocrine cause of hypertension.

Screening should be based on clinical judgment.

For as long as it has been described, Cushing’s syndrome has presented physicians with a problem. Harvey Cushing first described it in 1932, and the diagnosis, differential diagnosis and treatment of Cushing’s have remained a major challenge for endocrinologists ever since.

Patient is a 65-year-old white man with a past medical history significant for severe coronary artery disease, arrhythmias, hypertension, hyperlipidemia, anxiety and type 2 diabetes. He was referred to the endocrine clinic for the evaluation of a right adrenal nodule. The adrenal mass was found incidentally on an abdominal CT performed as part of an evaluation for epigastric pain caused by peptic ulcer disease.