Adrenal News

New data support a relationship between evening cortisol recovery and marital satisfaction, leisure time, paid work and housework among dual-income families.

Despite increased adherence to glucocorticoid stress dosing guidelines, patients with adrenal insufficiency are still at risk for acute adrenal failure, according to data published in the Journal of Pediatrics.

Hypertension in those who have aldosterone-producing adrenal adenomas may be traced to genetic mutations in the potassium channel KCNJ5, data suggest.

The widespread use of radiological technologies and hormonal evaluations has boosted physicians’ ability to detect adrenal incidentalomas and distinguish functional or primary malignancies from benign masses, thereby providing more treatment options and better outcomes, recent data suggest.

Phase 3 study data indicate that mifepristone alleviated hypertension, improved glucose intolerance and was well tolerated by patients with Cushing’s syndrome.

Fewer than 10% of adults with congenital adrenal hyperplasia receive care from an endocrinologist, and there is no standard treatment for these patients, researchers in the United Kingdom have found.

Researchers have identified variations of a gene that are associated with the development of pheochromocytomas.

Aldosterone appears to be a major stimulator of the brain centers that control the vascular system and blood pressure, research suggests.

Women with diagnosed and undiagnosed autoimmune Addison’s disease are at increased risk for preterm birth, low birth weight and other unfavorable pregnancy outcomes, according to results of a Swedish population-based cohort study.

A task force convened by the Endocrine Society has created a new clinical practice guideline for congenital adrenal hyperplasia that recommends universal newborn screening for severe steroid 21-hydroxylase deficiency, followed by confirmatory tests.