Adrenal News

The FDA today approved mifepristone to control hyperglycemia in adults with endogenous Cushing’s syndrome who have type 2 diabetes or glucose intolerance and are not candidates for surgery or who have not responded to prior surgery.

Canadian Pediatric Endocrine Group

Patients with primary aldosteronism appeared to have elevated parathyroid hormone levels compared with those with essential hypertension, according to recent data.

Cortisol levels decreased in infants from the time of waking to 30 minutes after waking, according to study results.

Once-daily dual-release hydrocortisone was associated with a more circadian-based serum cortisol profile compared with the thrice-daily dose tablets in patients with adrenal insufficiency.

Endocrinologists face many challenges when treating patients with Cushing’s syndrome. Diagnosis can be difficult because many of the disease’s characteristics, such as obesity, depression and hypertension, are also common in the general population.

Mothers who have HIV and were treated before and after birth with the protease inhibitor lopinavir-ritonavir were more likely to have infants with adrenal dysfunction compared with a zidovudine-based regimen, according to a preliminary report published online this week.

A 29-year-old man was seen 2 years ago to transfer his care from pediatric to adult endocrinology. He was diagnosed at birth with classic congenital adrenal hyperplasia from 21-hydroxylase deficiency with glucocorticoid and mineralocorticoid deficiencies.

13th European Congress of Endocrinology

13th European Congress of Endocrinology