Adrenal News

A little more than 1% of adults in a general screening population who underwent a CT scan had adrenal tumors, and more than two-thirds of all tumors were nonfunctioning, according to a study published in the Annals of Internal Medicine.

SAN DIEGO — Osilodrostat is associated with improvements in physical manifestations of hypercortisolism and reductions in mean body weight and BMI in adults with Cushing’s syndrome, according to a speaker.

SAN DIEGO — Compared with placebo, levoketoconazole improved cortisol control and serum cholesterol levels for adults with endogenous Cushing’s syndrome, according to results from the LOGICS study presented here.

SAN DIEGO — In this video exclusive, Saleh Aldasouqi, MD, FACE, ECNU, discusses the false high or false low results of certain hormone tests for people who take high doses of biotin in beauty and energy supplements, for example.

Adrenal gland volume is greater among adults with type 2 diabetes than without diabetes and might serve as a biomarker of metabolic status, according to study findings.

The use of an immunohistochemistry‒guided targeted amplicon sequencing approach using formalin-fixed, paraffin-embedded tissue detected somatic mutations in more than 70% of cortisol-producing adenomas, according to study data.

Current evidence does not support dehydroepiandrosterone use to improve women’s menopausal symptoms, sexual health and overall well-being, and long-term use may lead to estrogenic adverse events, according to a review article.

Even low-dose treatment courses of inhaled corticosteroids for asthma can lead to adrenal suppression including fatigue, headache, abdominal pain, vomiting and psychiatric symptoms, according to a study published in Nature Medicine.

Mild autonomous cortisol secretion is prevalent in nearly half of adults with benign adrenal tumors and can increase the risk for hypertension and type 2 diabetes, according to study data published in the Annals of Internal Medicine.

The FDA approved the steroidogenesis inhibitor levoketoconazole for adults with Cushing’s syndrome for whom surgery is not an option or has not been curative, according to an industry press release.