Adrenal News

Individuals with congenital adrenal hyperplasia are at greater risk for cardiovascular and metabolic morbidity, with the highest risk seen in women and girls and in men and boys with certain genotypes, according to research in The Journal of Clinical Endocrinology & Metabolism.

Pregnant women had higher concentrations of corticotropin-releasing hormone in the cerebrospinal fluid compared with nonpregnant women, according to recent study findings published in The Journal of Clinical Endocrinology & Metabolism.

Critically ill patients in intensive care who receive early IV feeding are no more likely to experience adrenal insufficiency than patients who receive only tube feeding for the first 7 days, according to research in The Journal of Clinical Endocrinology & Metabolism.

Neurocrine Biosciences recently announced suspension of two planned clinical studies of NBI-77860, a selective non-peptide corticotropin releasing factor 1 receptor antagonist with potential for decreasing symptoms of classic congenital adrenal hyperplasia.

Adolescents and young adults with congenital adrenal hyperplasia are more likely to have increased amounts of abdominal fat tissue, putting them at greater risk for metabolic syndrome and cardiovascular disease, according to research in The Journal of Clinical Endocrinology & Metabolism.

A nearly four times higher risk for breast cancer in adulthood was found among women exposed to higher levels of DDT compared with those exposed to lower levels before birth, according to recent study findings published in The Journal of Clinical Endocrinology & Metabolism.

Women and young adults with nonfunctioning pituitary adenoma have a higher risk for premature death, particularly women with hypopituitarism or diabetes insipidus, according to research in The Journal of Clinical Endocrinology & Metabolism.

A cross-sectional association exists between average weekly alcohol consumption and higher levels of adiponectin, but alcohol intake does not appear to be linked to changes in total circulating adiponectin concentrations over time, according to recent findings.

In Ecuadorian adults, growth hormone receptor deficiency without growth hormone counterregulation appears to result in enhanced insulin sensitivity and avoidance of diabetes, according to recent study findings published in The Journal of Clinical Endocrinology & Metabolism.

In children born very preterm, higher levels of growth hormone in early infancy may be partly responsible for cognitive deficits seen in these children at school-age, according to recent findings.