Adrenal News

Many adults with hypertension do not undergo the necessary screening for primary aldosteronism, and those who do often receive suboptimal care, making the condition a “major public health issue” that needs to be addressed by physicians, according to an updated clinical practice guideline released by the Endocrine Society.

Exposure during middle age to atrial natriuretic peptide within the high normal range appears to be associated with a reduced risk for insulin resistance after 16.5 years of follow-up.

Patients with primary aldosteronism tend to have a higher prevalence of malignancies than patients with hypertension, according to recent study findings.

Men with high baseline cortisol levels that decrease in response to stress had lower bone mineral content and bone mineral density measurements than men with lower baseline cortisol levels that increase with stress, according to research in Bone.

In shift workers, circadian misalignment appears to cause a decrease in glucose tolerance, independent of behavioral or circadian phase effects, according to recent findings.

Salivary cortisone measurements strongly correlate with serum cortisol measurements and may serve as a noninvasive alternative to estimate serum cortisol and serum free cortisol, according to research in The Journal of Clinical Endocrinology & Metabolism.

Adults with Prader-Willi syndrome randomly assigned the MetAP2 inhibitor beloranib for 6 months saw a significant reduction in both body weight and hyperphagia-related behaviors when compared with those assigned placebo, according to phase 3 trial results released by the drug’s developer, Zafgen.

In premenopausal women with breast cancer treated with chemotherapy, subsequent bone loss may be predicted by higher baseline follicle-stimulating hormone levels, according to recent study findings published in The Journal of Clinical Endocrinology & Metabolism.

In patients with pseudohypoparathyroidism type 1A, obesity appears to be caused mainly by decreased resting energy expenditure, rather than increased energy intake or endocrine dysfunction, according to recent findings.

Adults with primary hyperparathyroidism and low vitamin D levels are likely to have high levels of serum parathyroid hormone, indicating more severe disease; however, more severe disease does not affect bone structure or volumetric bone mineral density, according to research in The Journal of Clinical Endocrinology & Metabolism.