Adrenal News

A scoring system based on clinical signs and a late-night salivary cortisol test accurately predicted Cushing’s syndrome in at-risk patients, with only one missed case, according to recent findings.

Patients with nonfunctional adrenal tumors are at a higher risk for incident diabetes than individuals without adrenal tumors, according to findings published in the Annals of Internal Medicine.

People with hypertension may not be at increased risk for primary aldosteronism compared with people without hypertension; however, people with resistant hypertension should be screened for primary aldosteronism, recent study data suggest.

Sex-specific associations appear to exist between androgens, estradiol and sex hormone-binding globulin and sleep quality, with dehydroepiandrosterone-sulphate linked to wake after sleep onset in women and androstenedione associated with the Epworth Sleepiness Scale in men, according to recent findings.

Recent findings indicated associations between low cortisol levels, metabolic disorders and cardiovascular risk factors among individuals with mood disorders.

In menopausal women, hormone level, race, BMI, lifestyle and psychosocial factors predict distinct patterns regarding the timing and severity of vasomotor symptoms, according to findings.

Adult patients with severe growth hormone deficiency previously treated for acromegaly saw an increased fracture risk after 6 years of growth hormone replacement therapy, whereas those previously treated for Cushing’s disease did not experience the same risk, according to a recent observational study.

Elevated late-night salivary cortisol may serve as an early biochemical marker of recurrent Cushing’s disease, and prompt intervention may result in clinical benefits for people with Cushing’s disease, according to recent study findings.

The likelihood of malignancy, the presence and degree of hormone overproduction, and the age, health and preference of the patient should determine the appropriate response to adrenal incidentalomas discovered through imaging, according to a clinical practice guideline released by the European Society of Endocrinology.

Antral follicle count, or AFC, a biomarker of ovarian reserve, declines in women who are fertile and infertile with increasing age, although the decline is higher in women with infertility, study data show.