Adrenal News

Adults with pheochromocytoma or paraganglioma are nearly five times more likely to experience a vertebral fracture, a hallmark of osteoporosis, when compared with adults with nonfunctional adrenal tumors, according to findings published in Bone.

Children and adolescents with congenital adrenal hyperplasia, or CAH, diagnosed early via a neonatal screening program and treated with hydrocortisone had normal psychometric intelligence and executive function compared with population controls, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

An analysis of unselected adults who underwent a CT scan suggests that those who had an unsuspected adrenal tumor were more likely to have type 2 diabetes, although it is unclear whether cortisol secretion influences any risk, according to findings published in The Journal of Clinical Endocrinology & Metabolism.

Obesity is common at diagnosis of pituitary adenoma in childhood and may persist despite successful treatment, according to findings published in Clinical Endocrinology.

Higher glucocorticoid doses for adults with congenital adrenal hyperplasia may be associated with lower bone mineral density, especially among women and those prescribed prednisolone, according to findings published in Clinical Endocrinology.

Approximately 20% of a cohort of adults with Cushing’s syndrome experienced at least one thrombotic event after undergoing pituitary or adrenal surgery, with the highest risk observed for those undergoing bilateral adrenalectomy, according to findings from a retrospective analysis published in the Journal of the Endocrine Society.

In 2019, Healio readers were interested in fertility preservation for men on testosterone therapy, the wonders of metformin, possible associations between statins and diabetes, a new osteoporosis drug and more. 

A combination of the captopril challenge test and saline infusion test improves the diagnostic accuracy for primary aldosteronism when compared with a saline infusion test alone, according to findings published in Clinical Endocrinology.

Frailty, loosely defined as a syndrome of physiologic decline in late life, is most often characterized by marked vulnerability to adverse health outcomes. Often associated with aging, frailty is typically characterized by slowness, weakness, fatigue and unintended weight loss, and is considered an indicator of overall health for older adults.

Hospitalized adults with primary or secondary adrenal insufficiency are more likely to be admitted to the ICU, be readmitted at 30 days or 1 year, and have a longer overall length of stay when compared with controls, according to findings from a propensity score-matched study published in the European Journal of Endocrinology.