VIDEO: Experts debate drivers of PCOS
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ATLANTA — In this video exclusive, Andrea E. Dunaif, MD, lays out the positions for insulin vs. androgens as the cause of polycystic ovary syndrome.
Dunaif is the Lillian and Henry M. Stratton Professor of Molecular Medicine and chief of the Hilda and J. Lester Gabrilove division of endocrinology, diabetes and bone disease at the Icahn School of Medicine and the Mount Sinai Health System in New York. She is also an Healio | Endocrine Today Co-editor.
In a debate session at the ENDO Annual Meeting, Dunaif presented the side for androgens against Ricardo Azziz, MD, MPH, MBA, who argued for insulin. Azziz is professor of obstetrics and gynecology, medicine, and health care organization and policy at the University of Alabama at Birmingham School of Medicine and School of Public Health and chief science and strategy officer and executive vice president of operations, strategy and scientific affairs at the Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center.
“Really there are multiple causes of PCOS, and some of our recent work has shown there are actual subtypes of PCOS that have distinct genetic architecture,” Dunaif said. “I think over the next 5 to 10 years we’re going to see genetics leading us to a much better understanding of what the disorders are that we’re now calling PCOS.”
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