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June 28, 2021
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Recent updates in obesity care, treatment

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To highlight recent treatment approvals, study findings and other important research results on obesity released amidst the COVID-19 pandemic, Healio compiled a list of game-changing coverage on obesity from the past year.

These articles include news on the FDA’s recent approval of semaglutide (Wegovy, Novo Nordisk) for chronic weight loss, the efficacy of supervised Nordic walking in patients with obesity, the use phenotype-guided obesity interventions determined by a blood test and more.

FDA approves once-weekly semaglutide for weight loss

The FDA approved once-weekly semaglutide injection for chronic weight management in adults with obesity or with overweight and at least one weight-related condition, according to an agency press release. Read more.

Supervised Nordic walking improves aerobic capacity, muscle strength in obesity

Adults with overweight or obesity had improved aerobic capacity and muscle strength after 6 months of supervised Nordic walking and maintained the improvements during 6 months of unsupervised training, according to study data. Read more.

Novel obesity classifications can aid in tailoring weight-loss treatments

Phenotype-guided obesity interventions, determined by a blood test, can double weight loss for patients compared with standard obesity care, according to a presenter at the Obesity Medicine Association 2021 virtual conference. Read more.

Old genetic discoveries may reveal ‘new tricks’ for treating obesity

Genetic modifiers — many discovered in the late 1990s — can be “harnessed” to better understand the processes and mechanisms behind weight gain and one day even regulate appetite, according to a speaker. Read more.

Metabolic improvements seen 26 weeks after fecal microbiome transfer for teens

Fecal microbiome transfer led to a mean reduction in android-to-gynoid fat ratio and a resolution of metabolic syndrome in a cohort of adolescents with obesity, according to randomized controlled trial data published in JAMA Network Open. Read more.

Combination liraglutide plus exercise improves weight-loss maintenance in obesity

A combination regimen of moderate to vigorous exercise plus daily liraglutide treatment resulted in better weight loss and improved weight maintenance compared with either treatment alone, according to data from a head-to-head trial. Read more.

Data support avoiding pregnancy for 1 year after bariatric surgery

Women who become pregnant in the year after bariatric surgery are more likely to experience higher rates of preterm birth and low birth weight compared with similar women who delayed pregnancy, a retrospective data analysis shows. Read more.

Mild obesity doubles risk for respiratory failure in COVID-19

Adults with any degree of obesity are more than twice as likely to experience respiratory failure and four times as likely to experience ICU admission when diagnosed with COVID-19 compared with similar adults without excess weight. Read more.

Different forms of sugar influence hunger response in young adults

Table sugar may be less efficient in provoking a satiety response compared with oral glucose, and individual biological factors also influence peripheral hormone responses to sucrose vs. glucose consumption, study data show. Read more.