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December 31, 2019
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Top news in NAFLD of 2019: screening, treatment and the end of biopsies

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Nonalcoholic fatty liver disease — and its more severe stage, nonalcoholic steatohepatitis, in particular — has surpassed alcoholism as a cause of cirrhosis and is on its way to becoming the No. 1 reason for liver transplantation in the United States. It is frequently associated with obesity, insulin resistance, diabetes and other metabolic risk factors.

Popular articles about NAFLD posted on Healio this year addressed screening, treatment and therapies in the pipeline.

Early action required for prevention, management of fatty liver in type 2 diabetes

At least half of all individuals with type 2 diabetes also have NAFLD, setting the stage for a worse metabolic profile and greater cardiovascular risks. Currently, there are no drugs approved to treat NAFLD.

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What is the best way to screen very high-risk patients for fatty liver or fibrosis?

Safe, accurate and easier-to-perform blood tests are needed to make diagnosis in the clinic easier.

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Highlighted liver 
Nonalcoholic fatty liver disease — and its more severe stage, nonalcoholic steatohepatitis, in particular — has surpassed alcoholism as a cause of cirrhosis and is on its way to becoming the No. 1 reason for liver transplantation in the United States.
Source: Adobe Stock

AI tool for NAFLD could ‘make biopsies history’

In this video exclusive, Christos S. Mantzoros, MD, PhD, discusses a new artificial intelligence and machine learning tool for nonalcoholic fatty liver disease prediction.

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Screen for fatty liver as a diabetes complication

In this Q&A, Kenneth Cusi, MD, FACP, FACE, discusses the recent rise in fatty liver disease and its connections with obesity and diabetes, describes how to screen for the condition and outlines current and future treatments.

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NASH more likely, liver fibrosis less likely with increasing C-peptide levels in type 2 diabetes

Adults with type 2 diabetes and higher C-peptide levels are more likely to develop simple nonalcoholic fatty liver disease and nonalcoholic steatohepatitis compared with those with lower levels.

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Blood test differentiates between NAFLD, NASH

A novel combinations of glycans, lipids and hormonal variables can simultaneously diagnose the presence of nonalcoholic fatty liver or nonalcoholic steatohepatitis with up to 90% accuracy.

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