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Dyslipidemia prevalence rising, awareness low among Chinese adults
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The rate of dyslipidemia is steadily increasing among Chinese adults, with low HDL cholesterol and hypertriglyceridemia reported as the most common lipid abnormalities, according to study findings.
Ling Pan, MD, of the renal division, department of medicine at First Affiliated Hospital of Guangxi Medical University, China, and colleagues analyzed survey results from 43,368 adults providing lipid profile data as part of the China National Survey of Chronic Kidney Disease, conducted from 2007 to October 2010 (25,169 women; mean age, 50 years; 55.8% urban residents). Participants completed on-site screenings (including blood and urine samples) and questionnaires. Dyslipidemia was defined according to the 2007 Chinese Guidelines on Prevention; cutoff values were 6.22 mmol/L for total cholesterol, 4.14 mmol/L for LDL, 1.04 mmol/L for HDL and 2.26 mmol/L for triglycerides. “Dyslipidemia awareness” was defined as participants who self-reported having the condition.
After adjustment, total prevalence of dyslipidemia was 34%; 7.5% had elevated total cholesterol; 15.3% had low HDL; 8% had elevated LDL; 12.2% had hypertriglyceridemia. Prevalence was higher overall in men vs. women (42% vs. 32%; P < .001); however, women aged at least 60 years had a higher prevalence vs. men (50% vs. 45.3%). Researchers noted the prevalence of dyslipidemia increased with age in both men and women (P < .001 for both).
Researchers found dyslipidemia prevalence varied by location, with a higher rate among urban residents vs. rural residents (35.1% vs. 26.3%). Within the cohort, 31% were aware of the condition; 19.5% were receiving treatment; control population was 8.9%. In multiple logistic regression analysis, researchers found that increasing age (OR = 1.01; 95% CI, 1.01-1.014), male sex (OR = 1.41; 95% CI, 1.32-1.51), obesity (OR = 1.42; 95% CI, 1.35-1.51), cardiovascular disease (OR = 1.34; 95% CI, 1.13-1.6), diabetes (OR = 1.96; 95% CI, 1.76-2.18), hypertension (OR = 1.48; 95% CI, 1.39-1.58) and hyperuricemia (OR = 2.22; 95% CI, 2.06-2.4) were independent risk factors for dyslipidemia.
“[The] awareness, treatment and control rate are not optimistic,” the researchers wrote. “There is an increased need for closely monitoring and controlling high risk factors, including postmenopausal women, unhealthy lifestyle populations and patients with chronic noncommunicable diseases. Free screening protocols, increased publicity and lifestyle modifications should be equally emphasized.” – by Regina Schaffer
Disclosure: The researchers report no relevant financial disclosures.
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