Immunodermatology News

Biological pathways are disrupted among patients with hidradenitis suppurativa, which suggests that inflammatory pathways, pathways of leucocyte activation and signaling, and innate immune responses require more study, according to researchers.

DESTIN, Fla. — In a session here at Congress of Clinical Rheumatology, Joseph F. Merola, MD, MMSc, of Harvard Medical School and Brigham and Women’s Hospital, shared the dermatology approach to cutaneous lupus erythematosus, as well as valuable skin elements of dermatomyositis.

AbbVie announced that the FDA has approved Skyrizi, an interleukin-23 inhibitor for treating moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy.

Among patients with juvenile dermatomyositis, calcinosis was associated with longer active disease duration, disease severity and clinical features such as lipodystrophy and joint contractures, according to data published in Pediatric Rheumatology.

The FDA awarded more than $18 million in grants over the next 4 years to fund clinical trials of medical products intended to treat patients with rare diseases.

The FDA has approved rituximab for the treatment of adult patients with moderate-to-severe pemphigus vulgaris, a rare autoimmune blistering disease that affects the skin and mucous membranes, according to a company press release.

BOSTON — Rheumatologists, gastroenterologists, dermatologists, immunologists and other health care providers who care for patients with immune-mediated inflammatory diseases will gather at the Interdisciplinary Autoimmune Summit in Boston this weekend for a collaborative discussion of treatment strategies.

The FDA has rejected approval of Celltrion’s biologics license applications for Truxima, a proposed rituximab biosimilar, and Herzuma, a proposed trastuzumab biosimilar, issuing Complete Response Letters for both products.

Myeloablative autologous stem cell transplantation improved long-term clinical outcomes, including overall survival and event-free survival, among patients with diffuse cutaneous systemic sclerosis, according to findings published in the New England Journal of Medicine.

One patient in a large cohort of individuals with autoimmune blistering diseases developed pneumocystis pneumonia, suggesting that routine prophylaxis of this condition may not be warranted in this patient population, according to recent findings.