Dermatitis News

Variant frequency in the filaggrin gene was strongly associated with race among pediatric patients with atopic dermatitis.

In a clinical study, Kamedis cream with botanical extracts was 44% more effective in treating atopic dermatitis than Kamedis cream without botanical extracts and 23% more effective than an over-the-counter third-party brand, according to a press release from the company.

NEW YORK — There are now multiple target treatments to utilize in patients with atopic dermatitis, but there is still a very large unmet need for better treatment in this disease, according to Emma Guttman-Yassky, MD, PhD, a Sol and Clara Kest professor of dermatology at Icahn School of Medicine at Mount Sinai in New York.

In patients with pruritus, the itch severity scale demonstrated a significantly higher retest reliability and stronger correlation with the itch-related quality of life compared with three well-known unidimensional scales.

Physicians should inform patients with hidradenitis suppurativa about an increased risk for inflammatory bowel disease, according to research in JAMA Dermatology.

Cara Therapeutics announced the commencement of a phase 2 trial for oral Korsuva for the treatment of pruritus in patients with atopic dermatitis.

When discussing the risk for all skin cancers, it is important to consider family history of melanoma in a first-degree relative, according to Erin X. Wei, MD, staff physician at Brigham and Women’s Hospital and instructor of dermatology at Harvard Medical School, and colleagues in the most popular Healio Dermatology story last week.

In a phase 4 study, young patients with mild to moderate eczema aged 3 months to younger than 24 months tolerated treatment with crisaborole ointment 2%, which is consistent with previous clinical trials, according to Pfizer.

Researchers recommend new nomenclature of “chronic pruritus of unknown origin,” or CPUO, a diagnostic workup and classification to help increase the understanding of chronic pruritus.

In the top Healio Dermatology story from last week, inflammation plays a key role in male and female pattern hair loss, according to a phase 2, open-label clinical trial in patients with androgenetic alopecia.