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Cutaneous Oncology News
First-line pembrolizumab effective, safe in unresectable cutaneous squamous cell carcinoma
Pembrolizumab monotherapy appeared to be effective and safe as first-line treatment for patients with unresectable cutaneous squamous cell carcinoma, according to results of a phase 2 study published in Journal of Clinical Oncology.
31-gene expression profile test may aid in melanoma stratification
The 31-gene expression profile test demonstrated consistent sensitivity in identifying patients with melanoma at risk for recurrence or distant metastasis, according to a study.
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Indoor tanning decreased in high school students following age restrictions
The prevalence of indoor tanning decreased in high school students following age restrictions on the practice in New Jersey, according to a study.
Steroids may improve mogamulizumab efficacy for cutaneous T-cell lymphoma
The combination of mogamulizumab and topical steroids conferred favorable outcomes to patients with previously treated cutaneous T-cell lymphoma, according to study results presented at Society of Hematologic Oncology Annual Meeting.
GEP tests show poor prognostic ability in recurrent stage I melanoma
Two gene expression profile tests for cutaneous melanoma often failed to accurately identify recurrent stage I disease, according to a study.
Topical calcineurin inhibitors did not increase skin cancer risk in atopic dermatitis
Among a large cohort of patients with atopic dermatitis, treatment with topical calcineurin inhibitors demonstrated no association with elevated risk for keratinocyte carcinoma, according to a study.
Mutational heterogeneity may be common in melanoma
Mutational heterogeneity was observed in almost 20% of melanoma tumors, according to a study.
Phase 3 trial of regimen for advanced melanoma misses primary endpoint
A randomized phase 3 trial designed to evaluate the addition of spartalizumab to two targeted agents for the treatment of certain patients with advanced melanoma failed to meet its primary endpoint, according to the agent’s manufacturer.
Skin cancer risk included in hydrochlorothiazide label change
A label change for the diuretic hydrochlorothiazide has been approved to include a small risk for non-melanoma skin cancer, the FDA announced in a press release.
Nivolumab plus ipilimumab, pembrolizumab may be most cost-effective in advanced melanoma
Nivolumab plus ipilimumab- and pembrolizumab-based therapies may be the most cost-effective approaches in advanced melanoma, according to a study.
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Headline News
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