Cutaneous Oncology News

Dermoscopy allows for thorough observation of morphologic features not visible to the naked eye in melanoma screening, according to a speaker at the South Beach Symposium Medical Dermatology Summit.

Patients’ response to anti-CTLA-4 or anti-PD-1 checkpoint therapy for advanced melanoma, and their incidence of immune-related adverse events of grade 3 or higher, were similar regardless of preexisting autoimmune disease, according to data.

Patients with a stage III melanoma mutation treated with dabrafenib plus trametinib had longer restricted mean survival times compared with placebo, according to an analysis of a phase 3 trial presented at Maui Derm for Dermatologists.

Circulating tumor DNA measurements before and during treatment could help guide selection of therapy for patients with BRAF V600-mutant unresectable or metastatic melanoma, according to study results published in The Lancet Oncology.

Patients treated with cemiplimab for advanced cutaneous squamous cell carcinoma had improvements to quality of life, pain and other symptoms, according to a presentation at South Beach Symposium Medical Dermatology Summit.

The FDA granted regular approval to cemiplimab-rwlc for patients with locally advanced basal cell carcinoma who were previously treated with or ineligible for treatment with a hedgehog pathway inhibitor.

Patients with basal cell carcinoma who discontinued hedgehog inhibitors had differing odds for reinitiation that varied by grace period, according to a presentation at Maui Derm for Dermatologists.

The FDA granted fast track designation to TH1902 for treatment of certain patients with sortilin-expressing cancers, according to the agent’s manufacturer.

Patients with advanced cutaneous squamous cell carcinoma had an “increasing, clinically meaningful” duration of response with cemiplimab, according to results from a phase 2 study presented at Maui Derm for Dermatologists.

Dermoscopy training and education should be prioritized in resident education to increase melanoma detection, according to a study published in JAMA Dermatology.