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Cutaneous Oncology News
Female patients on immune checkpoint inhibitors at risk for dermatologic adverse events
Female patients with melanoma on immune checkpoint inhibitor therapy exhibited higher rates of dermatologic adverse events compared with male patients, according to a study presented at AAD VMX 2021.
Data show widespread adoption of active surveillance for certain patients with melanoma
Most adults with sentinel lymph node-positive cutaneous melanoma underwent active ultrasound surveillance rather than surgery across academic medical centers in the U.S., Europe and Australia, according to study results published in Cancer.
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Roswell Park Comprehensive Cancer Center names dermatology chair
Gyorgy Paragh, MD, PhD, has been appointed Lawrence P. & Joan Castellani family chair in dermatology at Roswell Park Comprehensive Cancer Center.
cSCC tumors upgraded during Mohs micrographic surgery often more challenging
Cutaneous squamous cell carcinomas that were upgraded during Mohs micrographic surgery were more likely to present clinical challenges, according to a study.
Tumor-infiltrating lymphocytes show ‘dramatic’ results in metastatic melanoma
More than 80% of patients with heavily pretreated metastatic melanoma experienced tumor shrinkage after receiving the adoptive cell therapy lifileucel, according to results of a phase 2 study.
Tumor mutational burden predicts treatment response among women, not men, with melanoma
Tumor mutational burden predicted immune checkpoint inhibitor response among women, but not men, with melanoma, according to findings presented during the virtual American Association for Cancer Research Annual Meeting.
Thiazides associated with increased risk for skin cancer in older adults
Adults aged over 65 years who took thiazides for hypertension had an increased risk for keratinocyte carcinoma and melanoma, according to results of a population-based cohort study.
Tebentafusp improves OS in advanced uveal melanoma
Tebentafusp significantly prolonged OS compared with immune checkpoint inhibitors and other standard therapies among previously untreated patients with metastatic uveal melanoma, results of a randomized phase 3 study showed.
Survival after Mohs surgery for invasive melanoma associated with treatment facility
Early-stage invasive melanoma excised with Mohs micrographic surgery at academic and top decile-volume facilities was associated with improved long-term survival, according to a study published in JAMA Dermatology.
Cutaneous immune-related adverse events often precede noncutaneous events
Cutaneous immune-related adverse events are an early sign of immune-mediated toxic events, and dermatologists can play a role in screening for more severe events, according to a study.
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