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Cutaneous Oncology News
Researchers identify skin darkening enzyme that could help prevent skin cancers
Researchers at Massachusetts General Hospital have discovered a skin pigment mechanism that could be developed into a topical drug aimed at reducing skin cancer risk, according to a study published in Cell.
Novel electron beam therapy approach yields swift response in T-cell lymphoma lesions
A novel technique of low-dose rotational total skin electron beam therapy provided a fast and durable response in a small cohort of patients with skin lesions associated with cutaneous T-cell lymphoma.
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FDA grants priority review to Keytruda for stage II resected high-risk melanoma
The FDA granted priority review to pembrolizumab for adjuvant treatment of certain patients with high-risk melanoma.
FDA grants fast track designation to nemvaleukin alfa for mucosal melanoma
The FDA granted fast track designation to nemvaleukin alfa for treatment of mucosal melanoma.
Melanoma incidence, prevalence have increased in US in recent decades
While melanoma incidence and prevalence in the U.S. increased between 1990 and 2019, mortality rates remained stable over that time, according to findings from a mathematical model.
St. Jude registry identifies melanoma subgroups, assists in treatment choices
A pediatric melanoma registry developed at St. Jude Children’s Research Hospital has helped researchers improve the classification of pediatric melanocytic tumors.
Head, neck melanomas more likely to need tissue-rearranging reconstruction vs. carcinomas
Tissue-rearranging reconstruction is needed more in melanomas of the head and neck, which have high local recurrence rates, compared with keratinocyte carcinomas, according to a study.
Cutaneous T-cell lymphoma overall survival associated with TCR clonality, flow cytometry
Overall survival was lower for patients with early-stage cutaneous T-cell lymphoma who had low-level blood involvement, according to a study.
Metformin may reduce basal cell carcinoma risk
Metformin, even in low doses, may be associated with a decreased risk for basal cell carcinoma, according to a study.
FDA approves Keytruda for locally advanced cutaneous squamous cell carcinoma
The FDA expanded the approval of pembrolizumab to include treatment of patients with locally advanced cutaneous squamous cell carcinoma not curable by surgery or radiation, according to the agent’s manufacturer.
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