Popular topics this month: Hidradenitis suppurativa, atopic dermatitis

Victoria K. Shanmugam

Recent articles on hidradenitis suppurativa and atopic dermatitis have garnered the most pageviews so far this month at Healio Dermatology.

In the most popular article, biological pathways were disrupted in patients with hidradenitis suppurativa, which suggests that inflammatory pathways, pathways of leucocyte activation and signaling, and innate immune responses require more study, according to researchers.

Alterations in pathway activation found in hidradenitis suppurativa

“This highlights the importance of the immune system in [hidradenitis suppurativa] and identifies deficient or suppressed antimicrobial peptide levels as a possible biomarker in [hidradenitis suppurativa],” Victoria K. Shanmugam, MD, of the division of rheumatology at George Washington University School of Medicine and Health Sciences, told Healio Dermatology. Read more.

New regional dermatoses reported in some patients taking dupilumab

In a cohort of adults with atopic dermatitis who were taking dupilumab, nearly a quarter of patients developed new regional dermatoses appearing mostly on the face. Read more.

Cyclosporin ‘moderately effective’ at inducing remission of alopecia areata

Adults with moderate to severe alopecia areata treated with cyclosporin had a greater reduction in Severity of Alopecia Tool score over time when compared with a placebo group, according to a study. Read more.

Both ivermectin, permethrin yield high clearance rates in scabies

In scabies treatment, oral ivermectin at 200 µg/kg may be associated with slightly lower rates of complete clearance after 1 week compared with 5% permethrin cream, but researchers found little or no difference in complete clearance by weeks 2 and 4. Read more.

Researchers suggest relationship between psoriasis and MS

Patients with multiple sclerosis are more likely to have prevalent or incident psoriasis, but the pathway that leads to both psoriasis and MS remains unclear. Read more.