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Two hyaluronic acid fillers show comparable efficacy, safety in lip enhancement

Lip fullness and aesthetic appearance outcomes were similar for two hyaluronic acid lip fillers, according to recent findings.

The researchers compared outcomes for patients with very thin to moderately thick lips. Thirty-one patients were treated with hyaluronic acid-RK, and 29 underwent treatment with hyaluronic acid-JV. The maximum dose for both was 3 mL.

The main outcome measure was improvement by one or more points on a five-point scale.

Results showed that 1.54 mL of hyaluronic acid-RK was required to reach the primary outcome measure, and 1.94 mL of hyaluronic acid-JV was required to reach this endpoint (P < .001).

Both treatment approaches yielded similar lip fullness and global aesthetic improvement, according to the findings. For lip fullness, 6-month results showed that 60% of patients in the RK group and 57.7% of those in the JV group demonstrated improvements. Similarly, 12-month results showed that 71.4% of those in the RK arm and 76% of those in the JV arm reported aesthetic improvement in blinded evaluations. Other findings from 12 months showed that 85.7% of those in the RK group and 86.2% of those in the JV group felt more attractive.

More than 95% of patients in each group reported that they would recommend the treatment.

Tolerability was similar for both treatment approaches, with 19.4% of patients in the RK arm and 37.9% of those in the JV arm experiencing treatment-associated adverse events. However, no serious events were reported for either treatment. – by Rob Volansky

Disclosure: The authors report no relevant financial disclosures.