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Time to steady state in fat graft volume may be longer than thought
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The time to reach steady state for fat graft volume was 2.2 years, which was much longer than anticipated, according to recent findings.
The aim of the retrospective longitudinal cohort study was to investigate the association between covariates and fat graft retention in a cohort of 208 patients who underwent the procedure after VS ablative surgery between 2006 and 2015. The final analysis included 108 patients who were divided into high- and low-baseline volume groups with a cutoff volume of 16 mL.
Total resorption did not occur in any patient during follow-up. Significant evidence of resorption over time was, however, reported (P < .0001). The researchers used 324 examinations to model the fat graft retention trajectory. They estimated that steady state in volume occurred after 806 days (95% CI, 645-956 days). At that point, a 50.6% fat graft retention was observed (95% CI, 46.4%-54.7%).
Over time, fat graft retention was significantly higher among men compared with women (P < .0005). Transplant volume and graft retention rate showed no significant association. – by Rob Volansky
Disclosure: The researchers report no relevant financial disclosures.
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