November 21, 2016
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FDA action, lidocaine and pediatric AD studies top dermatology reads for week

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The FDA’s clearance of Syneron Candela's microneedling device for appearance of cellulite was among the most-read articles of the past week on Healio.com/Dermatology.

Other widely read articles included findings that intracutaneous lidocaine local anesthesia for skin cancer excision and reconstruction had less risk than conscious sedation or general anesthesia, and survey results showing that great variation exists in prescribing practices of systemic agents for pediatric atopic dermatitis:

Lidocaine local anesthesia has less risk than conscious sedation or general anesthesia

Intracutaneous lidocaine local anesthesia for skin cancer excision and reconstruction had no reported toxicity in survey results, with less risk than conscious sedation or general anesthesia, according to research published in Dermatologic Surgery.

Murad Alam, MD, MSCI, of the departments of dermatology, otolaryngology and surgery at Northwestern University, Chicago, and colleagues conducted an online survey of 1,175 members or fellows of the American College of Mohs Surgery between June and October 2014. Read more

Wide variation exists in prescribing practices of systemic agents for pediatric atopic dermatitis

A survey of physicians in the United States and Canada found that there is great variation in prescribing practices of systemic agents to treat atopic dermatitis, according to results published in the Journal of the American Academy of Dermatology.

Researchers developed an online multiple response survey to collect information on demographics, clinical practice data, systemic agent selection and barriers to systemic medication use for patients with recalcitrant pediatric atopic dermatitis. Read more

FDA grants clearance to Syneron Candela's microneedling device for appearance of cellulite

Syneron Candela announced in a press release that it has received FDA 510(k) clearance for Profound, its minimally invasive, fractional radiofrequency microneedling device, when using the SubQ handpiece and cartridge for improving the appearance of cellulite.

The device is indicated for use in dermatologic and general surgical procedures for electrocoagulation and hemostasis. Read more

Vitiligo rates increase after hematopoietic stem cell transplantation

Patients who underwent hematopoietic stem cell transplantation had a significantly increased rate of vitiligo development compared with controls, according to study results published in the Journal of the American Academy of Dermatology.

Researchers used the Korean National Health Insurance Claims Database to perform a nationwide, population-based cohort study between 2009 and 2013. Read more

Xeljanz shows promise as treatment for alopecia areata in adolescents

Treatment with Xeljanz in adolescents with alopecia areata resulted in significant hair regrowth for the majority of the patients, with mild adverse events, according to recently published study results.

Brent A. King, MD, PhD, assistant professor of dermatology, Yale School of Medicine, and colleagues studied 13 adolescent patients (median age 15 years; 77% male) with alopecia areata treated with Xeljanz (tofacitinib, Pfizer) between July 2014 and May 2016 at a tertiary care center clinic. Read more