Psoriasis, melanoma studies top dermatology reads for week

Research finding that patients with psoriasis being treated with Remicade had no significant change in clinical response when switching to an infliximab biosimilar was among the most-read articles of the past week on Healio.com/Dermatology.

Other widely read articles included study findings that although white patients had a higher incidence of cutaneous melanoma, overall survival was significantly lower for minority patients compared with whites:

Patients with psoriasis effectively switch from Remicade to infliximab biosimilar

Patients with psoriasis being treated with Remicade had no significant change in clinical response and experienced minor adverse events when switching to an infliximab biosimilar, according to recently published study results.

Researchers studied two cohorts of patients with moderate-to-severe psoriasis who were treated between July 1, 2015, and Jan. 20, 2016 at the University of Turin in Italy. Read more

No significant difference found between Otezla, methotrexate in treating psoriasis

There were no statistically significant differences found in efficacy between Otezla and methotrexate for moderate-to-severe psoriasis, according to recently published study results.

April W. Armstrong, MD, MPH, of the Keck School of Medicine at University of Southern California, Los Angeles, and colleagues conducted a literature review to identify trials that included patients with moderate-to-severe plaque psoriasis who reported 75% improvement in Psoriasis Area and Severity Index score (PASI 75) from baseline to week 16. Read more

Filler rhinoplasty produces short-term outcomes comparable with surgery

Filler rhinoplasty produced temporary outcomes that were comparable to surgical augmentation rhinoplasty, according to recently published study results.

Researchers in Seoul, South Korea, retrospectively reviewed the records of 242 patients (91.3% female; mean age, 31 years) who revisited a clinic between 2 and 8 weeks after initial hyaluronic acid filler rhinoplasty. Read more

Atopic dermatitis increases risk for comorbidities, dermatologist reports

Atopic dermatitis increases the risks for short-term and long-term systemic comorbidities, according to information presented at the American Academy of Dermatology Summer Meeting in Boston.

“Although it affects the skin, eczema is not just skin-deep,” Jonathan Silverberg, MD, PhD, MPH, FAAD, assistant professor in dermatology, medical social sciences and preventive medicine at the Northwestern University Feinberg School of Medicine in Chicago, reported in an AAD press release. Read more

Overall survival for melanoma lower in minority patients compared with whites

Although white patients had a higher incidence of cutaneous melanoma, overall survival was significantly lower for minority patients compared with whites, according to research recently published in the Journal of the American Academy of Dermatology.

Researchers used the National Cancer Institute Surveillance, Epidemiology and End Results database to gather population data on 96,593 patients (54.7% male) diagnosed with primary cutaneous melanoma from 1992 to 2009 in 13 registries in the United States. Read more