Kybella, Botox studies top dermatology reads for week

Study results finding that Kybella demonstrated efficacy in treating submental fat, and may be an alternative to surgical treatment, was among the most-read articles of the past week on Healio.com/Dermatology.

Other widely read articles included findings that Patients with mild glabellar lines at rest achieved elimination of the resting lines following repeated Botox treatment and that women with a personal history of mild-to-severe psoriasis may have an elevated risk for squamous cell carcinoma:

Kybella may be an effective alternative to surgical treatment for submental fat

Kybella demonstrated efficacy in treating submental fat, and may be an alternative to surgical treatment, according to recently published study results.

Shannon Humphrey, MD, of the University of British Columbia and Carruthers & Humphrey, Vancouver, British Columbia, and colleagues conducted a phase 3, double-blind trial of 516 adults (86.2% women; mean age, 47.9 years; mean BMI, 29.3 kg/m2) with moderate-to-severe submental fat. Patients were randomly assigned to Kybella (deoxycholic acid, Allergan), also known as ATX-101, or placebo. Read more

Specific allergen immunotherapy found not to be effective for atopic eczema

There was a lack of consistent evidence that specific allergen immunotherapy is effective for treating atopic eczema, according to published study results.

Inclusion criteria included randomized controlled trials of specific allergen immunotherapy (SIT) using standardized allergen extracts and compared with placebo or control for treating atopic eczema in patients with allergic sensitization. Read more

Repeated Botox treatments improve glabellar lines at rest

Patients with mild glabellar lines at rest achieved elimination of the resting lines following repeated Botox treatment, according to recently published study results.

Alastair Carruthers, MD, of the department of dermatology and skin science, University of British Columbia, Vancouver, and colleagues extracted data from a 1-year repeat treatment measurement including two 4-month randomized, placebo-controlled double-blind clinical studies followed by an 8-month open-label study. Read more

Researchers review wrinkles occurring through facial compression during sleep

Facial compression during sleep results in wrinkles, and possibly contributes to skin expansion, according to research recently published in the Aesthetic Surgery Journal.

Goesel Anson, MD, FACS, of Anson, Edwards & Higgins, Plastic Surgery Associates, Las Vegas, and colleagues conducted a literature review related to wrinkle development and biomechanical changes occurring “in response to intrinsic and extrinsic influences.” Read more

Psoriasis linked to increased risk for SCC in women

Women with a personal history of mild-to-severe psoriasis may have an elevated risk for nonmelanoma skin cancer, particularly squamous cell carcinoma, according to recently published study results.

The study included 157,934 participants. The personal history of psoriasis at baseline was 1.8% among the 63,054 participants from the NHS with 1,204 SCC cases and 8,899 BCC cases documented after follow-up. Read more