Vitiligo research includes noncultured cellular grafting, combination therapy

Recent World Vitiligo Day events raised awareness and support of patients with the disease.

Research on vitiligo treatment reported on Healio.com/Dermatology has included noncultured cellular grafting successfully achieving repigmentation, and combination therapy with topical calcineurin inhibitors and excimer laser/light proving more effective than excimer laser/light monotherapy:

Noncultured cellular grafting successfully achieves repigmentation for vitiligo

Repigmentation was maintained up to 60 months in more than 80% of patients with vitiligo who were treated with noncultured cellular grafting, according to published study results.

Researchers reviewed data for 177 patients (mean age, 34.4 years; 54.8% female) with vitiligo who underwent noncultured cellular grafting between March 2006 and December 2012 at the National Skin Center in Singapore. Read more

Researcher discusses new phototherapy standards for vitiligo

WASHINGTON — Recent phototherapy standards for treating vitiligo were part of a symposium presentation at the American Academy of Dermatology Annual Meeting.

Iltefat Hamzavi

Iltefat Hamzavi, MD, senior staff physician, Henry Ford Hospital, Detroit, and Hamzavi Dermatology, reviewed the different treatment options for vitiligo, including topical, phototherapy and oral treatments. Read more

Anti-PD-1 therapy for melanoma associated with eczema, vitiligo

Anti-programmed cell death-1 therapy for patients with metastatic melanoma was associated with cutaneous adverse events, including lichenoid reactions, eczema and vitiligo, according to recently published study results.

Researchers conducted a prospective and retrospective observational study with unresectable stage IIIC/IV metastatic melanoma treated with Keytruda (pembrolizumab, Merck) or Opdivo (nivolumab, Bristol-Myers Squibb) between May 1, 2012 and Feb. 1, 2015 at Westmead Hospital, Sydney, Australia. Read more

Excimer laser/light combined with topical calcineurin inhibitors effective for vitiligo

Combination therapy with topical calcineurin inhibitors and excimer laser/light was more effective than excimer laser/light monotherapy in treating vitiligo, according to the study results.

Researchers in Korea conducted searches of Medline, Embase and Cochrane databases from inception through Dec. 15, 2014, to identify randomized controlled trials assessing the efficacy of excimer laser/light (EL) alone or in combination with topical agents for vitiligo. Read more

Vitiligo associated with survival in patients receiving Keytruda for metastatic melanoma

The onset of vitiligo may be associated with clinical benefit in patients with metastatic melanoma who were treated with Keytruda, according to study results published in JAMA Dermatology.

Researchers in France conducted a prospective study of patients with metastatic melanoma from Jan. 1, 2012 to Sept. 24, 2013, at the Cancer Campus of Gustave Roussy Institute. Read more