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Seven recent developments in psoriasis
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Recent developments in psoriasis reported on Healio.com/Dermatology include a study finding that pediatric psoriasis development is linked to infections but not antibiotics, and research linking psoriasis severity to vascular inflammation beyond cardiovascular risk factors.
Other developments include research presented at the American College of Rheumatology Annual Meeting showing that bariatric surgery may improve the symptoms of psoriasis and the FDA’s approval of Enstilar for the topical treatment of plaque psoriasis in adults:
1. Infections, but not antibiotics, associated with pediatric psoriasis
While infections were associated with the development of pediatric psoriasis, there was no independent risk association with antibiotics, according to study results published in JAMA Dermatology.
“We found that antibiotics were no more strongly associated with newly diagnosed psoriasis in children than infections managed without antibiotics,” the researchers wrote. Read more
2. Psoriasis severity linked to vascular inflammation beyond CV risk factors
Severity of psoriasis appears to be associated with vascular inflammation independent of risk factors for vascular disease, according to recent findings.
In a prospective observational study, researchers evaluated 60 patients withpsoriasis (median age, 47.5 years; 28 men and 32 women) and 20 matched controls (median age, 41 years; 13 men and seven women). Read more
3. VIDEO: Bariatric surgery may improve symptoms of psoriatic arthritis and psoriasis
SAN FRANCISCO — At the American College of Rheumatology Annual Meeting, Soumya M. Reddy, MD, co-director, NYU Psoriatic Arthritis Center, and assistant professor of medicine, New York University School of Medicine, discussed results of a study that found excessive weight loss aided by bariatric surgery was linked to improved symptoms in patients with psoriatic arthritis and psoriasis. Watch video
4. Challenges of pediatric psoriasis include better standards of care
A recent clinical review addressing treatment of pediatric psoriasis identified several gaps in the current standard of care, including differences in symptom appearance compared with adult patients and the risk for long-term comorbidities.
Amy Paller
5. Immunosuppressed patients have increased risk for stroke immediately after herpes zoster
SAN FRANCISCO — The risk of stroke is greatest for patients with complex herpes zoster, particularly those affecting the head and neck, according to a presentation during the Plenary Session of the American College of Rheumatology Annual Meeting, here. However, the research suggest that “prompt antiviral therapy for herpes zoster is associated with lower subsequent stroke with risk consistent with previous studies.”
Leonard H. Calabrese, DO, and colleagues used the 2006 to 2013 Medicare database with 100% of the patient sample having rheumatoid arthritis, inflammatory bowel disease, psoriatic arthritis, psoriasis or ankylosing spondylitis. Read more
6. National Psoriasis Foundation holds congressional briefing on skin of color and psoriasis
The National Psoriasis Foundation recently held a congressional briefing to focus on African-Americans, Asians, Latinos and other non-Caucasians with psoriasis and the challenges they face, according to a press release.
Amy McMichael
Panelists included Amy McMichael, MD, chair of dermatology at Wake Forest Baptist Medical Center and the Maya Angelou Center for Health Equity. Read more
7. FDA approves Enstilar for topical treatment of plaque psoriasis in adults
LEO Pharma announced in a press release that Enstilar has been approved by the FDA for the topical treatment of plaque psoriasis in adults.
Enstilar (calcipotriene and betamethasone dipropionate) is an alcohol-free foam formulation in a pressurized spray can that allows for application across large areas of plaque psoriasis, according to the release. Read more