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Skin care product containing 0.1% retinol improves acne vulgaris lesions, improves QoL
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VANCOUVER, British Columbia — Inflammatory lesions and post-inflammatory lesions greatly improved in those with acne treated with a dermo-cosmetic skin care product containing 0.1% retinol, according to research presented at the 23rd Annual World Congress of Dermatology.
Sixty patients aged 12 to 35 years old with mild-to-moderate acne on the face presented with at least 10 retentionnal lesions, five inflammatory lesions and at least one post-inflammatory lesion.
The product was applied daily in the evening for 42 days.
The Investigator Global Assessment (IGA) of acne severity and a four point scale were used to evaluate product tolerance and efficacy.
Patients self-evaluated the global improvement of acne, their quality of life and the cosmetic acceptability via questionnaire.
Retentionnal and inflammatory lesions decreased after 21 and 42 days of use.
Patients and dermatologists rated the product as efficacious at reducing post-inflammatory lesions from day 22.
The mean IGA improved from mild to almost clear at days 22 and 43.
Quality of life improved for the patients and most reported good agreement of the product.
Reference :
Gurdak M, et al. Clinical evaluation of the tolerance and efficacy of a dermo-cosmetic skin care product containing retinal 0.1% in subjects presenting acne vulgaris. Presented at: 23rd World Congress of Dermatology; June 8-13, 2015; Vancouver, British Columbia.