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Seven recent developments involving pediatric dermatology
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Recent study findings involving pediatric dermatology included the potential association between moderate-to-severe atopic dermatitis with central obesity and increased blood pressure in children.
Research results presented on Healio.com/Dermatology also included children of melanoma survivors not adhering to optimal sun protection, as well as the possible combination of eczema and lack of sleep contributing to a negative effect on children’s growth:
1. Pediatric atopic dermatitis potentially associated with central obesity, increased BP
Moderate-to-severe atopic dermatitis was found to have a potential association with central obesity and increased blood pressure in children and adolescents, according to published study results.
Jonathan I. Silverberg
Jonathan I. Silverberg, MD, PhD, MPH, and colleagues studied 132 patients with active moderate-to-severe atopic dermatitis and 143 controls recruited from seven U.S. dermatology referral centers between April 1, 2009, and Dec. 31, 2012. Read more.
2. Changes in nevi were poor predictors of melanoma in children
Monitoring changes in nevi may not be a useful approach to melanoma detection in children and may lead to unnecessary biopsies in this population, according to study findings.
Researchers utilized data from the Pinkus Dermatopathology Laboratory database and the HealthCore Integrated Research Database to estimate the number of nevus biopsies in patients 19 years or younger in the U.S. between 2009 and 2013. Read more.
3. Children of melanoma survivors shown to not adhere to optimal sun protection
Beth Glenn
Researchers at the University of California, Los Angeles, reported recently that children of melanoma survivors are not adhering to optimal sun protection recommendations, with more than 40% experiencing sunburn in the past year.
Beth Glenn, PhD, and colleagues identified and surveyed 300 Latino and non-Latino white melanoma survivors with children 17 years old and younger during a 3-year period, according to a press release. Read more.
4. Eczema, insufficient sleep could affect growth in small percentage of children
Amy S. Paller
Eczema in childhood or adulthood generally was not associated with short stature; however, a small percentage of children between the ages of 10 and 11 with eczema and insufficient sleep experienced a negative effect on growth, according to study findings.
Jonathan I. Silverberg, MD, PhD, MPH, and Amy S. Paller, MD, MS, reviewed data for 264,326 children and adolescents and 85,311 adults from nine U.S. population-based studies from 2003 to 2012. Read more.
5. Doxcycline plus adapalene/benzoyl peroxide comparable to oral isotretinoin for severe acne
Doxycycline plus adapalene/benzoyl peroxide was found to be comparable to oral isotretinoin in a combined efficacy and safety profile for the treatment of patients with severe nodular acne, according to study results.
Researchers conducted a multicenter, randomized, investigator-blinded study of 266 patients between the ages of 12 and 35 years with severe facial acne vulgaris. Read more.
6. ECG not beneficial as beta-blocker pretreatment for infantile hemangioma
Electrocardiogram did not provide additional value as a pretreatment tool prior to initiation of beta-blocker treatment in patients with infantile hemangiomas and unremarkable cardiovascular history, a normal heart rate and blood pressure, researchers found.
Researchers retrospectively analyzed data from 109 patients with infantile hemangiomas who were treated with propranolol or atenolol between July 2008 and August 2012. Read more.
7. Study links facial port-wine stain patterns with Sturge-Weber syndrome risk
Specific upper-facial port-wine stain patterns in infants were associated with an increased risk of Sturge-Weber syndrome, according to published study results.
Researchers in France prospectively studied consecutive cases of upper-facial port-wine stains larger than 1 cm2 within the ophthalmic division of trigeminal nerve distribution in 66 infants. Read more.