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Palmoplantar psoriasis has greater impact on skin-related QoL, self-care

Compared with moderate-to-severe plaque psoriasis, palmoplantar psoriasis is independently associated with a greater impact on skin-related quality of life; greater impairment of mobility, self-care and usual activities; and a greater dependency on topical medications.

In a cross-sectional study, researchers compared patient-reported outcomes for 1,153 patients with severe plaque psoriasis and 66 patients with palmoplantar psoriasis who were receiving systemic or light therapy.

A higher percentage of patients with palmoplantar versus plaque psoriasis were on oral systemic therapy (55% vs. 37%, respectively).

The researchers found no significant differences between the levels of pain, anxiety/depression and self-perceived health state between the two groups.

Patients with palmoplantar psoriasis were 2.08 times more likely to report at least a moderate impact on skin-specific health-related quality of life than patients with plaque psoriasis, according to the researchers.

Additionally, patients with palmoplantar psoriasis were significantly more likely to report problems with mobility, self-care and usual activities.

Palmoplantar patients were also 2.81 times higher to report heavy topical prescription usage compared with patients who had severe plaque psoriasis, the researchers found.

Disclosure: See the study for a full list of all authors’ relevant financial disclosures.