Surgery News

Two analyses of large randomized controlled trials suggest that participants not taking medications as prescribed may influence treatment effects and impact study findings, researchers reported.

Norton score upon admission is a marker of short‐ and long‐term mortality and should be considered as a risk stratification tool for adults who are candidates for surgical aortic valve replacement, researchers reported.

Compared with aspirin alone, aspirin plus ticagrelor was associated with reduced risk for vein graft failure and increased risk for clinically important bleeding in patients who underwent CABG, according to a meta-analysis.

The risk for stroke and other poor outcomes was similar in patients with postoperative atrial fibrillation after noncardiac surgery and in patients with AF not associated with surgery, researchers reported.

A collaborative network of pediatric cardiac intensive care teams significantly decreased rates of in-hospital cardiac arrest over 18 months using a low-technology prevention practice bundle, independent of secular trends, data show.

Among patients undergoing elective CABG, infusion of high-dose tranexamic acid modestly reduced the need for red blood cell transfusion and was noninferior to low-dose infusion regarding safety, findings show.

Compared with endovascular therapy, thromboendarterectomy surgery was associated with better 1-year patency, but longer hospital stays, in patients undergoing revascularization for common femoral artery lesions, researchers reported.

A 4% albumin solution for priming and perioperative IV volume replacement solution in CABG did not reduce risk for 90-day major adverse events compared with standard Ringer’s acetate solution, researchers reported.

Among adults without anemia presenting for elective cardiac surgery, iron deficiency was not associated with fewer days alive and at home when assessed at postoperative day 30 or 90, researchers reported in The Lancet Haematology.

Early revascularization may confer mortality benefit in patients with moderate to severe myocardial ischemia identified on nuclear stress testing, regardless of left ventricular ejection fraction, researchers reported.