TCT
STEMI-RADIAL: Radial approach enhanced outcomes in PCI
MIAMI — Results from the STEMI-RADIAL trial presented at TCT 2012 have shown that using the radial approach vs. the femoral approach for PCI decreased major bleeding, access site complications and improved overall clinical outcomes in patients with STEMI.
No benefit noted with postconditioning after primary PCI
MIAMI — New data from the POST trial demonstrate that ischemic postconditioning after primary PCI did not improve myocardial reperfusion or clinical outcomes vs. PCI alone, Joo-Yong Hahn, MD, said here at TCT 2012.
RESPECT, PC trials examine outcomes with PFO closure device
MIAMI — Using an investigational patent foramen ovale closure device was superior to medical management alone for the prevention of recurrent stroke, according to data from the RESPECT trial.
ADAPT-DES: Low responsiveness to clopidogrel after DES predicted stent thrombosis, MI
MIAMI — One-year results from the ADAPT-DES registry suggest that clopidogrel hyporesponsiveness after implantation of a drug-eluting stent is an independent predictor of stent thrombosis and MI at 1 year.
PARADOX: Smoking influences pharmacokinetics and pharmacodynamics of clopidogrel
MIAMI — Smoking appears to affect the pharmacokinetics and pharmacodynamics of clopidogrel, but not prasugrel, according to results from the PARADOX trial.
FAME II: FFR-guided PCI cost effective vs. medical therapy
MIAMI — Results of a cost-effectiveness subanalysis of the FAME II trial suggest that fractional flow reserve-guided PCI was cost effective in terms of quality-adjusted life years compared with standard medical therapy alone in patients with stable CAD.