Genetics/Genomics News

Healthy adults with spherical hearts, identified through a deep learning analysis of cardiac MRI images, were 31% more likely to develop atrial fibrillation and 24% more likely to develop cardiomyopathy, researchers reported.

Genetic variants associated with CVD found incidentally during testing should be interpreted with caution using a framework that includes a multidisciplinary team of experts, according to a new scientific statement.

Assessing odds for subclinical ASCVD by midlife based on maternal inheritance of FH.

NEW ORLEANS — Black female carriers of the V122I genetic variant for cardiac amyloidosis have substantially higher CVD and all-cause mortality risk, which grows with age, compared with noncarriers, researchers reported.

Haptoglobin gene expression in the blood appeared associated with anthracycline-related cardiomyopathy among childhood cancer survivors, according to study results.

NEW ORLEANS — Causal artificial intelligence used to augment a polygenic risk score for CAD helped estimate how much individual patients must lower their LDL, systolic BP or both to overcome inherited risk for a major coronary event.

Researchers in China have identified specific gut microbiome bacteria that may influence risk for several subtypes of ischemic stroke, according to research published in the European Journal of Preventive Cardiology.

Emerging precision medicine therapies targeting the molecular causes of cardiomyopathy and HF may improve the outlook for pediatric patients with HF, according to a review published in Translational Pediatrics.

A healthy lifestyle was associated with reduced risk for CVD among adults with familial hypercholesterolemia regardless of their familial hypercholesterolemia mutation status, researchers reported.

Cardiometabolic multimorbidity and midlife onset of cardiometabolic disease are significantly associated with an increased risk for dementia, and genetic background may underlie this association, researchers reported.