CHD/Prevention News

Breast arterial calcification seen on routine mammograms, especially among younger women, is associated with increased risk for death and adverse cardiovascular outcomes, including heart failure, myocardial infarction and stroke, data show.

People with type 2 diabetes had twice the number of CVD events vs. matched counterparts, with events starting 3 decades before diagnosis, suggesting their elevated CVD risk may be attributable to factors tied to diabetes development.

CHICAGO — In patients with heterozygous familial hypercholesterolemia with high LDL despite being on optimal medical therapy, obicetrapib greatly lowered LDL levels compared with placebo, according to the results of the BROOKLYN trial.

SAN DIEGO — Semaglutide was superior to placebo in metabolic dysfunction-associated steatohepatitis resolution and improvement in fibrosis at 72 weeks, with a safety profile consistent with previous studies, according to late-breaking data.

CHICAGO — Black and Hispanic women who adhered to components of a Mediterranean-style diet were less likely to experience any adverse pregnancy outcome, regardless of overweight or obesity status, researchers reported.

Salt substitution intervention beginning at age 40 years was cost-effective among Chinese adults with prehypertension compared with antihypertensive drug treatment alone, according to findings published in Hypertension.

The GLP-1 receptor agonist semaglutide may not only add another therapeutic option for chronic kidney disease, but it could also lead to changes in the way clinicians treat the condition.

CHICAGO — Adults with elevated liproprotein(a) at high risk for a CV event saw substantial reductions over 12 weeks with muvalaplin, an investigational oral small molecule Lp(a) inhibitor, data from a phase 2 study show.

CHICAGO — People living in historically redlined neighborhoods with poor access to healthy foods were more likely to have type 2 diabetes, hypertension, coronary heart disease and obesity, researchers reported.

CHICAGO — Emailed messages emphasizing the CV benefits of influenza vaccination improved vaccine uptake among older and younger adults in Denmark, particularly among more vulnerable patients with a history of acute MI, researchers reported.