Kidney disease strongest predictor of sudden cardiac arrest for Hispanic/Latino adults
Click Here to Manage Email Alerts
Key takeaways:
- More than half of Hispanic or Latino adults with a sudden cardiac arrest had prior chronic kidney disease.
- Preexisting CVD, heavy drinking and diabetes were also predictors of sudden cardiac arrest.
Data from a population-based study show more than half of all Hispanic or Latino adults who experienced sudden cardiac arrest had a prior diagnosis of chronic kidney disease, with 20% on dialysis, researchers reported.
In an analysis of more than 1,400 adults (27% Hispanic or Latino) who had a sudden cardiac arrest (SCA) and more than 3,000 Hispanic or Latino controls, researchers also found that existing CVD, including stroke, atrial fibrillation, CAD and HF, as well as heavy drinking and type 2 diabetes, were also predictors of SCA.
“Among Hispanic/Latino individuals in our study who had a sudden cardiac arrest, we found an unexpectedly high proportion with chronic kidney disease (51%) and especially a high proportion on dialysis (20%),” Kyndaron Reinier, PhD, associate director of epidemiology in the Center for Cardiac Arrest Prevention at the Smidt Heart Institute, told Healio. “This may indicate that chronic kidney disease is a particularly important risk factor for sudden cardiac arrest in the Hispanic/Latino community. Our study also found that preexisting CVD, such as coronary artery disease and heart failure, increases risk for cardiac arrest among Hispanic/Latino adults. These findings are similar to previously reported findings for non-Hispanic white and Black individuals.”
In a case-control study, Reinier and colleagues analyzed data from 1,468 adult SCA cases, using the ongoing Ventura PRESTO study (2015-2021) in Ventura County, California. Researchers selected controls from 3,033 Hispanic or Latino participants who completed second visit examinations (2014-2017) at the San Diego site of the Hispanic Community Health Survey/Study of Latinos.
The findings were published in the Journal of the American Heart Association.
Among Hispanic or Latino SCA cases (n = 295) and frequency-matched controls (n = 590; 70.2% men; mean age, 63 years), the following clinical variables were associated with SCA in models adjusted for age, sex, and other clinical variables: chronic kidney disease (OR = 7.3; 95% CI, 3.8-14.3), heavy drinking (OR = 4.5; 95% CI, 2.3-9), stroke (OR = 3.1; 95% CI, 1.2-8), AF (OR = 3.7; 95% CI, 1.7-7.9), CAD (OR = 2.9; 95% CI, 1.5-5.9), HF (OR = 2.5; 95% CI, 1.2-5.1) and diabetes (OR = 1.5; 95% CI, 1-2.3).
“Prevention and treatment of kidney disease among Hispanics/Latinos may reduce risk of sudden cardiac arrest,” Reinier told Healio. “Our study is the first to evaluate risk factors for sudden cardiac arrest among U.S. Hispanics and Latinos. Our findings should be replicated in another population.”
For more information:
Kyndaron Reinier, PhD, can be reached at kyndaron.reinier@cshs.org.
Collapse
Read more about
Click Here to Manage Email Alerts