Top news of TCT 2022: PCI vs. CABG in multivessel CAD, PROTECTED TAVR results and more

Healio and Cardiology Today have compiled a list of the most-read news in CV intervention from TCT 2022.

Readers were most interested in the long-term findings from the BEST trial; a trial of two transcatheter mitral valve repair systems for degenerative mitral regurgitation; cerebral embolic protection during transcatheter aortic valve replacement; and more.

BEST: Few differences in long-term outcomes between PCI, CABG in multivessel CAD

At a median follow-up of 11.8 years, most outcomes did not differ between PCI with an everolimus-eluting stent and CABG in patients with multivessel CAD, according to new data from the BEST trial. Read more

Pascal noninferior to MitraClip for treatment of degenerative mitral regurgitation

A novel mitral valve transcatheter edge-to-edge repair system was noninferior to an existing system in a head-to-head trial in patients with severe symptomatic degenerative mitral regurgitation. Read more

Ultrasound renal denervation lowers BP at 2 months vs. sham: RADIANCE II

Compared with a sham procedure, ultrasound renal denervation lowered BP in patients with resistant hypertension at 2 months, according to results of the RADIANCE II randomized trial. Read more

Cerebral embolic protection during TAVR did not reduce overall stroke

In PROTECTED TAVR, the largest-ever randomized trial of TAVR, cerebral embolic protection did not decrease incidence of periprocedural stroke. Read more

Extent of cardiac damage plays major role in quality of life after AVR

In patients with aortic stenosis, a greater degree of cardiac damage before transcatheter or surgical AVR increased the likelihood of poor quality of life outcomes after the procedure, researchers reported. Read more

Routine ultrasound improved femoral access; did not lower bleeding, vascular complications

Ultrasound-guided femoral access improved first attempt success in coronary procedures but did not reduce the occurrence of major bleeding and vascular complications vs. fluoroscopy alone, a speaker reported. Read more

FLASH registry: Mechanical thrombectomy confers good short-term outcomes in PE

In patients with intermediate- and high-risk pulmonary embolism, mechanical thrombectomy was safe and linked with good short-term hemodynamic and clinical outcomes. Read more

In all-comers registry of left main CAD, CABG linked to better survival vs. PCI

In the all-comers SCAAR registry of patients with left main CAD who underwent revascularization in Sweden, PCI was associated with higher mortality rates compared with CABG. Read more

Edge-to-edge valve repair may improve mortality in severe MR, cardiogenic shock

In a large registry analysis, transcatheter edge-to-edge mitral valve repair had a high rate of device success in patients with severe mitral regurgitation and cardiogenic shock. Read more

VIDEO: Mehran reviews late-breaking science at TCT

In the Healio video exclusive, Roxana Mehran, MD, discussed late-breaking research presented at TCT 2022, as well as the benefits of convening the meeting in person following the COVID-19 pandemic. Read more