Daily coffee intake may improve cardiac function, lower risk for mortality, stroke
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Daily coffee consumption may improve cardiac function and up to three cups per day was associated with lower risk for CV and all-cause death and stroke, according to data presented at the European Society of Cardiology Congress.
To understand the CV impact of daily coffee consumption at varying volumes, Judit Simon, MD, researcher and PhD candidate at Heart and Vascular Centre at Semmelweis University in Budapest, Hungary, and colleagues included 468,629 UK Biobank participants with no known heart disease (mean age, 56 years; 56% women; median follow-up, 11 years). Individuals were stratified based on levels of daily coffee consumption: none (22.1%), light to moderate (0.5 to 3 cups per day, 58.4%) and high (> 3 cups per day, 19.5%). A total of 30,650 participants underwent cardiac MRI for the assessment of cardiac structure and function.
During a press conference, Simon said after adjustment for all potential CV risk factors, light to moderate coffee consumption was associated with lower risk for all-cause death (HR = 0.88; 95% CI, 0.83-0.92; P < .001), CV death (HR = 0.83; 95% CI, 0.74-0.94; P = .006) and incident stroke (HR = 0.79; 95% CI, 0.63-0.99; P = .037) compared with no daily intake of coffee.
Moreover, the risk for all-cause and CV death and stroke was not higher in the high coffee intake group compared with the no intake group.
Among the subgroup who underwent cardiac MRI, researchers observed that any coffee consumption was associated with greater left and right ventricular volumes and increased LV mass compared with no coffee.
“Daily coffee consumption proved to be safe, as even more than three cups per day were not associated with adverse outcomes after a median follow-up of 11 years,” Simon said during the press conference.
“Our findings suggest that regular coffee consumption of up to three cups per day was associated with favorable cardiovascular outcomes, including lower risk of stroke, all-cause mortality and cardiovascular mortality,” Simon said. “The observed benefits might be partly explained by positive alterations in cardiac structure and function as assessed by standard cardiac magnetic resonance imaging.”