Cardiology Today’s Intervention top 5 articles posted in the past month

Cardiology Today’s Intervention compiled a list of the top 5 stories posted to Healio.com/Intervention in September.

This month, Cardiology Today’s Intervention readers were most interested in stroke prevention in patients with atrial fibrillation, the success of transfemoral transcatheter aortic valve replacement with a repositionable valve at 30 days, resheathable TAVR systems, in-hospital risks for patients with AF after PCI, the 9-month outcomes of covered stents for patients with occlusive iliac artery disease and much more.

Trial launches for next-generation LAA occlusion device for stroke prevention in patients with AF

The device (Amplatzer Amulet) is used to close the left atrial appendage, which, in patients with nonvalvular atrial fibrillation, can be the source of stroke-causing blood clots, according to a press release from St. Jude’s Medical.

The trial will take place at 100 sites in the U.S. and 50 sites internationally. Patients enrolled will be randomly assigned to receive either the Amplatzer Amulet occluder or an FDA-approved LAA closure device (Watchman, Boston Scientific), according to the release. Read More

Transfemoral TAVR with repositionable valve successful at 30 days

In patients with severe aortic stenosis, transfemoral TAVR with a repositionable valve appears to yield a high rate of device success, no moderate or severe residual aortic regurgitation, and low 30-day rates of major vascular complications, death and stroke, according to recent findings.

In the prospective study, researchers evaluated 110 patients (mean age, 81 years; 51% women) who underwent TAVR with the 23 mm (n = 20), 25 mm (n = 43) or 27 mm (n = 47) repositionable valve system (Lotus, Boston Scientific). The valve system is not yet approved for use in the United States. Read More

Resheathable TAVR system shows promise in symptomatic severe aortic stenosis

A novel TAVR system demonstrated safety and efficacy in the treatment of high-risk patients with symptomatic severe aortic stenosis, enabling safe repositioning and position optimization, according to recent findings.

In the prospective, single-arm, multicenter study, researchers evaluated 100 patients (mean age, 84.1 years; 95% women; median Society of Thoracic Surgeons Predicted Risk of Mortality score, 5.6) at high surgical risk with NYHA class II or greater severe aortic stenosis. Read More

AF confers risk for poor in-hospital outcomes after PCI

Patients with a history AF undergoing PCI display higher risk for in-hospital complications such as bleeding, HF, cardiogenic shock and mortality, according to a study published in the Journal of the American College of Cardiology.

Nadia R. Sutton, MD, MPH, from the department of internal medicine, division of cardiovascular medicine, University of Michigan, Ann Arbor, and colleagues analyzed patients from a large, prospective multicenter registry to determine a link between AF and adverse in-hospital outcomes. Read More

Covered stent confers positive 9-month outcomes in patients with occlusive iliac artery disease

LAS VEGAS — A balloon-expandable covered stent was associated with favorable clinical outcomes and good patency at 9 months in patients with iliac artery lesions, according to findings from the BOLSTER study.

Researchers assessed procedural success, patency and safety and efficacy outcomes of the covered stent (LifeStream, Bard Peripheral Vascular) in 155 patients with obstructive lesions in the iliac artery. Read More