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OVER: EVAR associated with lower post-procedural mortality
Most mortality occurred within 30 days of either procedure.
2009 Vascular Annual Meeting
Endovascular repair of abdominal aortic aneurysms was associated with lower mortality than open repair, according to the two-year results of a study.
Researchers for the Open Vs. Endovascular Repair (OVER) trial enrolled 881 patients and randomly assigned 444 patients to undergo endovascular abdominal aortic aneurysm repair (EVAR) for aneurysms ≤5 cm and 437 patients to open repair. All patients were physiologically and anatomically indicated to receive both procedures. The primary study outcome was mortality following the procedures.
According to the study results, there were 31 deaths (7%) in the EVAR group and 41 (9.4%) in the open repair group (P=.19). There were 10 (2.3%) deaths within 30 days of the procedure in the open repair group vs. one (0.2%) in the EVAR group (P=.006). There were also 13 deaths within 30 days or during hospitalization in the open repair group vs. two in the EVAR group (P=.004).
“Post-operative mortality was lower for EVAR than for open, and lower for both procedures than in earlier trials,” Frank A. Lederle, MD, a researcher with the Veterans Affairs Medical Center in Minneapolis, Minn., said in a presentation. “Secondary procedures and abdominal aortic aneurysm-related hospitalizations and claudication were more frequent after EVAR, but not significant. Longer-term data are needed to fully assess the relative merits of the two procedures.” – by Eric Raible
For more information:
- Lederle F. LB1. Presented at: Vascular Annual Meeting; June 11-14, 2009; Denver.