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EXPIRA
Thrombectomy with Export Catheter in Infarct-Related Artery During Primary PCI
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Trial evaluated thrombectomy plus PCI vs. standard PCI for improvement of myocardial blush grade in patients with STEMI.
Design: randomized, prospective
Patients: 256
Centers: 1
Countries: Italy
RESULTS: Patients in the thrombectomy group (n=88) had higher myocardial blush grades at follow-up vs. the conventional PCI group (n=87; 76.3% vs. 32.4%, P<.0001). They also reported that ST-segment resolution after PCI was higher in the thrombectomy group vs. the conventional group (80.0% vs. 37.5%, P<.01). Results from a substudy of 75 study patients with anterior MI using MRI suggested that microvascular damage and infarct size were reduced in the thrombectomy group vs. the standard PCI group. Cardiac death in the standard PCI group was higher than in the thrombectomy group at two-year follow-up (6.8% vs. 0.0%, P=.0001), and also that major adverse cardiac events were higher in the standard PCI group vs. the thrombectomy group (13.6% vs. 4.5%, P=.050).
Presented at AHA 2009.
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