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CARESS: no difference between carotid endarterectomy and stenting
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There was no difference between carotid artery stenting and carotid endarterectomy in patients with symptomatic and asymptomatic carotid artery stenosis, study results suggested.
cResearchers for the CARESS trial enrolled 397 patients into the study. Patients were then assigned to a carotid endarterectomy (n=254) or a carotid stenting (n=143) group. The primary endpoint of the study was all-cause mortality at 30 days. The primary endpoint occurred in 0.4% of patients in the endarterectomy group and 0% of patients in the carotid stenting group at 30 days (P=.45). At four years, all-cause mortality remained comparable between the endarterectomy group and the stenting group (21.2% vs. 18.7%; P=.83). The combined freedom-from-stroke or death rate at four years was also comparable between the endarterectomy and stenting groups (73.5% vs. 78.3%; P=.36).
The researchers reported a higher rate of restenosis in the carotid stenting group vs. the carotid endarterectomy group (14.7% vs. 5.9%; P=.01).
