Skin Disorders News

Filaggrin expression might be a novel biomarker for chronic idiopathic urticaria severity; and altered filaggrin expression has physiologic effects on transepidermal water loss and pH in the skin of patients with chronic idiopathic urticaria, recently published data suggest.

Associations between childhood atopic dermatitis, atopic disease, warts, and extracutaneous infections suggest that barrier disruption, immune disruption, or both contribute to susceptibility to warts and extracutaneous infections in children, according to researchers.

There is an increased prevalence for psychological or behavioral disorders and injury among children with atopic dermatitis, asthma, hay fever and food allergies, according to researchers.

Evidence has suggested but remains unclear that vitamin D deficiency is associated with allergic diseases, such as atopic dermatitis and asthma, in addition to higher levels of IgE sensitization, according to researchers.

Recent data provide evidence that the onset of upper airway edema symptoms occur as quickly as 30 minutes from onset to maximum airway involvement, suggesting patient education to avoid morbidity and mortality.

Symptoms associated with atopic dermatitis appeared to persist into the second decade of children’s lives and possibly longer, making it a probable lifelong illness, according to recent study results.

Atopic dermatitis was often associated with food sensitization among adult patients; and the percentage of sensitization to animal food allergens appeared significantly greater among those with severe atopic dermatitis, according to data.

In patients with severe cutaneous adverse reactions related to systemic antibiotics, the presence of underlying comorbidities may contribute to increased mortality, according to recent findings from Taiwan.

Results from a large phase 4 FDA postmarketing study suggest that omalizumab therapy is not associated with an increased risk for malignancy.

Evidence suggests that coagulation, fibrinolysis and accompanying systems have a role in chronic urticaria pathogenesis and that evaluating their biomarkers may aid in disease management, according to a review article published in Allergy.