Primary Immunodeficiency Disease News

A prototype point-of-care rapid screening device differentiated between low immunoglobulin G antibody levels associated with agammaglobulinemia and normal levels, according to a study published in Journal of Clinical Immunology.

Convalescent plasma appeared safe and effective for the treatment of COVID-19 among patients with primary antibody deficiency, according to a study published in Journal of Clinical Immunology.

The FDA approved immune globulin subcutaneous (human)-hipp, 16.5% solution, or cutaquig, for the treatment of children aged at least 2 years with primary humoral immunodeficiency, according to a press release.

Children with primary immunodeficiency reported fatigue that impacts their quality of life, and targeting this fatigue may improve their well-being, according to a study published in Journal of Clinical Immunology.

Deficiencies in the CARMIL2 gene can lead to a variety of immunodeficiency complications, including cutaneous and respiratory allergies, necessitating clinician attention and further research, according to a study published in Allergy.

Patients with primary immunodeficiencies demonstrated higher COVID-19 mortality rates than the general population, according to a study conducted in Turkey and published in Journal of Clinical Immunology.

Primary humoral immunodeficiencies appeared significantly associated with psychiatric disorders and suicidal behavior, according to study results published in JAMA Psychiatry.

Primary immunodeficiencies are a group of over 350 rare and chronic conditions in which genetic defects cause the immune system to function improperly.

Infants with newly diagnosed X-linked severe combined immunodeficiency, or SCID-X1, demonstrated multilineage engraftment of transduced cells after receiving lentiviral vector gene therapy and nonmyeloablative targeted busulfan conditioning, according to study findings published in The New England Journal of Medicine.