Primary Immunodeficiency Disease News

LOUISVILLE, Ky. — Patients with noninfectious complications of common variable immunodeficiency, such as gastrointestinal disease, malignancy and rheumatoid arthritis, had increased mortality risk, according to study results.

LOUISVILLE, Ky. — In this Healio exclusive, Brian T. Kelly, MD, MA, FACAAI, program chair of the American College of Allergy, Asthma & Immunology Annual Scientific Meeting, highlights key sessions and themes of this year’s meeting.

Healio compiled the most-read news in allergy, asthma and immunology posted in September.

The FDA granted priority review to a new drug application for leniolisib to treat activated phosphoinositide 3-kinase delta syndrome in adults and adolescents aged 12 years and older, according to a Pharming Group press release.

Children with pre-existing inborn errors of immunity may have higher mortality rates due to COVID-19 than children who do not have these errors, according to a study published in The Journal of Allergy and Clinical Immunology.

Tandem mass spectroscopy screenings for newborns can identify partial or delayed adenosine deaminase deficiencies, which can have potentially fatal complications, according to a review published in Annals of Allergy, Asthma & Immunology.

Including tandem mass spectroscopy in newborn screenings to identify adenosine deaminase deficiencies could save lives while adding negligible costs, according to a study published in Annals of Allergy, Asthma & Immunology.

The omicron variant of the SARS-CoV-2 virus presents unique challenges for patients with immunodeficiencies and their health care providers, according to a paper published in The Journal of Allergy and Clinical Immunology: In Practice.

People with inborn errors of immunity can receive COVID-19 vaccines with no greater risk for adverse events, according to a review published in Annals of Allergy, Asthma & Immunology.

Most children with a primary immunodeficiency experienced fatigue, which can be evaluated via a review of these patients’ charts and use of a generic questionnaire, according to a study published in Journal of Clinical Immunology.